Endocrine Abstracts

Context: Amiodarone is a widely used anti-arrhythmic medication, however associated with a 15-20% rate of thyroid adverse effects. Amiodarone-induced thyrotoxicosis (AIT) is a complex disease due to diagnostic difficulties and therapeutic challenges. AIT patients often receive initial therapy for thyrotoxicosis before admission to a referral center. Whether the first-line medical therapy (i.e. therapies for thyrotoxicosis at first diagnosis of AIT) may affect the outcome of AI...

Objectives: The primary objective was to study the prevalence and the risk factors of vertebral fractures (VFs) in acromegaly patients either at diagnosis of acromegaly or during the follow-up. The role of routine chest radiography for detecting VFs in acromegaly was also evaluated.Design and methods: A retrospective cohort study was performed on 60 consecutive acromegaly patients, in a tertiary referral center. The presence of VFs was firstly evaluated ...